Methotrexate or Ciclosporin

HI Tasha, after 30yrs + of dealing with psoriasis I have been completely clear twice. once whilst on enbrel a biological.... and now after being prescribed Capimune (ciclosprorin). And i was covered head to toes severely in guttate (brought on by using Amgevita a biological given me to treat my plaque ps, I was in an awful mess....till I was given ciclosporin 4wks and I am completely clear ...

The last time I was totally clear was when I was taking methotrexate for RA, I'm currently on Benepali for the same and the Psoriasis has never been worse!

I had several cycles of ciclosporin, my skin cleared up on each occasion but returned not long after treatment stopped. The regular blood tests were somewhat reassuring, albeit an inconvenience at times. I had varied side effects each time. On my last treatment I had bad problems with my kidneys, initially thought it was just a UTI then on looking at bloods etc the doc admitting me to hospital for treatment said they thought it was the drugs doing them damage. I'm fine now but it put me off them. In saying that, everyone has different results from trying a treatment. In terms of results nothing else cleared me up more effectively than ciclosporin but it's not an option any longer for me. I never did methotrexate so can't comment on it. Good luck with whatever you decide.

I have been in your position. I was at my worse when I was 18/19 and ended up covered but also bed bound for a little while till I got the option of tablets. I started taking cicolosporin then got put on methotrexate as they are smaller tablets. Both have similar side affects. Don’t be put off as they do help and give brilliant results. You will have regular bloods and kept a close on eye.

i was on acitretin for nearly a year the initial dose gave me severe headaches but it stopped doing its job after about a year so tried methotrexate did the same thing so now im on nothing and skin is so bad and I cant even walk dont know what to try next..maybe the blueberries?