Dupixent (Dupilumab) treatment
Posted Thu 29 Apr 2021 17.48 by Vicky
Hi, has anyone tried the Dupixent (Dupilumab) treatment at all. It is a biologic treatment that you inject yourself (like an epi-pen) every 2 weeks. I just wondered how good it was before I ask my consultant in a few months time, & can it be used long term, as I have read about it & it sounds amazing. Thank you!
2
Posted Thu 29 Apr 2021 17.53 by scarletsmummy
i have never heard of it being used for Psoriasis as its a treatment used for eczema
1
Posted Thu 29 Apr 2021 18.03 by lizziep (edited Thu 29 Apr 2021 18.04 by lizziep)
I agree with scareletmummy - I thought it` was only used for eczema - I googled it and it makes no mention of psoriasis.``
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Posted Fri 30 Apr 2021 03.40 by Yacht
A quick look at the dupilumab page on Wikipedia today makes absolutely zero mention of psoriasis. It blocks IL-4 and IL-13 signals, neither of which is used currently for psoriasis.
The most effective biologics for psoriasis, right now, appear to be risankizumab, guselkumab and ixekizumab.
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Posted Sat 1 May 2021 19.29 by Yacht
Etanercept has very low efficacy. Studies suggest just a 20% chance of getting 90% clearance (PASI 90).
Risankizumab, guselkumab and ixekizumab have around 70-75% chance of PASI 90.
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