Axisbiotix- Probiotic Therapy for Psoriasis

I am definitely going to try this! I really do believe that the gut plays a major role in our condition. The results f the study look really good and I loved the videos from the participants too.

I have just started using Symprove after considering it for a long time. I am on Apremilast and my skin has cleared somewhat but still flares up. I am 1 week in so will update my progress Ona new thread.

Hi. Therapy for Psoriasis? A probiotic therapy? I do not think that is correct is it? Found this elsewhere ……… Are there any approved health claims on probiotics? Answer : 'There are no approved health claims for probiotics.' 'Applications for health claims on probiotics have been submitted for evaluation to EFSA and no application has received a positive opinion. Therefore, no claims on probiotics are listed on the EU register as authorised for use. The probiotic claims that have been fully evaluated and rejected are listed as non-authorised on the EU register. ' …….. However I did not research personally. Have they made that headline claim above? Or is it just a misunderstanding by the poster? I’m struggling to find the company making that claim anywhere re “probiotic therapy for psoriasis “ Have they?

here is a reference to that company: https://www.proactiveinvestors.co.uk/companies/news/938291/skinbiotherapeutics-says-axisbiotix-subsidiary-has-commenced-enrolment-for-its-food-supplementconsumer-study-938291.html There was a thread on here from some people who claimed to have been on the trial and claimed to have seem amazing results. But of course we have no idea if those claims were true, or just from parties with a vested interest (eg shareholders). Strangely I cannot find that thread now, the search does not find it. It was not a clinical trial. Particpants gave their own judgements as to whether they had seen improvements and to what degree. Apparently they also sent photos to the people running the studies. But there was no formal trials involving control groups and objective assessments of the conditions. They would have to market it as a food supplement because it has not been clinically tested as a treatment. In the company blurb it was mentioned that this was done to get it to market more quickly, but of course it also avoids formal clinical trials. Ah, here is an up-to-date news item: https://www.proactiveinvestors.co.uk/companies/news/961777/skinbiotherapeutics-to-launch-psoriasis-targeting-food-supplement-on-october-29-961777.html The product was apparently developed by two medical scientists at (I think) Manchester University. A few minutes research showed me that one of them was, until recently, a shareholder and director of the parent company. Of course none of this means that the product does not deliver benefits.

Thank you. I did read that study and to be very honest, not sure how they made a commercialisation decision based upon it But with regards to a probiotic being a direct treatment/therapy for psoriasis , is that even a legal claim to make under EU law? The company speak about psoriasis in their advert, but they do not make such headlines claims as seen here etc . The only thing they directly refer to is gut biome , and suggest it could aid in healthy skin . That is a far different claim to what others make re a therapy etc for psoriasis https://youtu.be/7_SWXcKSE8Q Do you see what I mean? (After watch advert) The study does not claim anything much either. Apart from a good response (when deduct the fallout rate ), and no negative response choices to questions on questionnaire So I doubt the company would be referring to that and making any wild , if not illegal, claims re health benefit direct association from a probiotic Unless the study changed the whole face of the science as generally known today? Inconclusive and in its infancy of understanding I just think it is unfair if the company is getting misrepresented in headlines Basically a probiotic drink as per advertised? Not seeing much else attached

Apart from a theory on psoriasis and the gut microbiome I just think comparing some product that had a photo shoot study non-clinical, compared to tens of millions spent by companies going through all those clinical trials etc, well, the thread headline is a bit misleading But that is just imo of course I hope it does cure psoriasis and if lucky, every other disease known to man, in the next photo shoot study too On the other hand, if it can be claimed, and looking at the general ingredients of many probiotic products, couldn’t they all claim it?

If I had psoriasis I would test the company claims by trying the product for 2 months[1 month is actually free!] and then write my review rather than knocking the company with unfair and ill judged criticism. Why don't you give it a go and let us all know exactly how you got on? If money is a concern then let me know and I will refund you to the tune of a month's supply. a month's supply. Kind Regards

Is this the place to be really writing a review about a product that had no clinical trial?

I suggest the company maybe do a placing or something? And do a clinical trial ? If you are a Doctor ( I do not know), are you recommending it to patients via NHS advice? What is their guidance on said products ?

Why would you do a clinical trial as it would take years to get to market. The product works and is available now. What has the NHS got to do with anything, it’s an otc product, that’s like asking should I take strepsils for a sore throat!

Strepsils went through far more then a self assessment home photo shoot with a participant questionnaire that didn't allow negative responses /feedback . I take it you are not a doctor then with such a disdain for clinical trials ? If getting it to market was the most important aspect, sales person?

I don’t have a disdain for clinical trials, I just don’t see the point. How many probiotics go through clinical trials? It works and it’s available, what’s the problem. Do you enjoy people suffering from psoriasis, I don’t understand why you have such an objection to this product.

I don't have an objection but you do highlight something important " how many probiotics go through clinical trials?'' Exactly my point.

Quote from a UK forum EU guidelines say that the term "probiotic" implies a health benefit that could mislead consumers because the science surrounding them remains largely inconclusive', so how will company X convince the psoriasis community of the complete opposite? 3. Given that there are no authorised health claims for a probiotic on the EU Register, and given that the company appear to believe that their probiotic food supplement is of a significant benefit to psoriasis sufferers lives, how will they market their probiotic specifically to the psoriatic community without breaking EU regulations ?

Hi, I think i had an interesting article relevant sent me a few days ago. I don’t think I’m allowed to share it all. I know it’s not a clinical study, but the was a large scale one. They’re typically done with less than a dozen because these studies are usually about safety not efficiency. These results are brilliant. No clue no clinical trial is required if they’re no making specific claims. So I don’t see the problem the other chap does. The important thing is does axis biotic work? It seems it works exceptionally well. Consumer Study Following highly positive results from its consumer study in May 2021, SkinBioTherapeutics has driven ahead of the finalisation of the regulatory pathway and commercial strategy for AxisBiotix-Ps™. Key activities have included preparing and warehousing the finished product and commencing marketing before the upcoming launch, as well as establishing a supply chain. · Psoriasis + Participants in the study self-identified as suffering from psoriasis and at least one other skin condition. Of these, 80% reported a reduction in itchiness, and 85% reported that their skin felt less irritable. · Eczema Participants who self-identified as suffering only from eczema reported the following results: · 71% reported that their skin felt less itchy; · 71% reported that their skin felt less irritable; · 64% reported a reduction in redness; and · 64% a reduction in 'flaky patches' on their skin. · Acne and rosacea The small group of participants who self-identified with these conditions reported improvements to their skin conditions. However, due to the size of the group, a larger cohort would be needed before statistics are published. Through its subsidiary AxisBiotix Limited ("AxisBiotix"), SkinBioTherapeutics has begun receiving and storing finished products at its distribution centre in the Netherlands. The warehouse is 10,000sq metres and is located in Boxtel near Eindhoven. It has been carefully chosen for its proximity to the Company's formulation partner, Winclove and its distribution links to the US, UK and Europe. As a result, readying of the finished product is ahead of schedule for launch. Commercialisation will commence with a 'soft launch' of AxisBiotix-Ps™ on World Psoriasis Day, 29 October 2021. As previously announced, commercialisation will start in the UK and the US markets. Sales of the product will be restricted initially to a limited number of customers from the pre-registration list to ensure a robust and reliable supply chain. After that, access to the eCommerce website will be opened up on a broader basis to the remainder of the waiting list and the wider psoriatic population. As disclosed in the business update on 19 August 2021, excluding shipping and any duty costs, AxisBiotix-Ps™ will be marketed on a subscription basis and priced per sachet (including VAT) in the US at $2.00 (USD), in the UK £1.50 (GBP). Europe €1.80 (EUR) and sold in boxes containing 28 sachets. To create a ready-made market for the product at launch, the Company has been busy ramping up the product's profile with a multi-media marketing strategy to encourage pre-registration of interest from potential customers. This campaign has included multiple video testimonials from participants of the consumer study in May 2021, some of which can be seen HERE. Pre-registration remains open at this stage and can be accessed via the AxisBiotix website at axisbiotix.com/form.

But your point has no relevance, why does something that doesn’t need to go through clinical trials, have to go through clinic trials, just because you think it does? This product works and is helping people. Seriously, what is your point.

Quote NHS says psoriasis occurs when skin cells are replaced more quickly than usual. It's not known exactly why this happens However, Sbtx video imv implies that the cause is primarily missing strains of bacteria in the gut? So I guess thats good. Just a theory though right? Or do the nhs need to update their website?

Did you see the questionnaire? You couldnt give a negative response to any question . Only positive choices given How many started, and finished the study?